Sebaceous-immunobiology is orchestrated by sebum lipids

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Sebaceous-immunobiology is orchestrated by sebum lipids

The major role of sebaceous glands in mammals is to produce sebum, which coats the epidermis and the hair providing waterproofing, thermoregulation and photoprotection. However, as the need for these functions decreased along the evolutionary changes in humans, a relevant question has been raised: are sebaceous glands and sebum the remnants of our mammalian heritage or do they have overtaken a ...

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The principal activity of mature sebaceous glands is producing and secreting sebum, which is a complex mixture of lipids. Sebum composition is different among species and this difference is probably due to the function that sebum has to absolve. In human sebum there are unique lipids, such as squalene and wax esters not found anywhere else in the body nor among the epidermal surface lipids. Mor...

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Examination of lipids in human sebum by disk chromatography.

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Age and ethnic variations in sebaceous lipids

This study was conducted to compare lipid components of sebum from persons from three ethnic backgrounds-Caucasian, African American and Northern Asian. Men and women with no acne in two age groups (18‒25 y and 35‒45 y) were recruited. Skin surface hydration (SkiCon 200EX and NovaMeter), barrier function (Delfin VapoMeter), high-resolution clinical imaging, self-assessments and two pairs of seb...

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ژورنال

عنوان ژورنال: Dermato-Endocrinology

سال: 2017

ISSN: 1938-1980

DOI: 10.1080/19381980.2017.1375636